Simparica TRIO requires a prescription from your veterinarian. He seemed to get a little better over the next week until he woke at 5am vomiting and having diarrhea and very lethargic. While she has not had seizures, trembling, or spasms, sometimes she just squeals and jumps up for no obvious reason. Our vet gave us this medication for our 8 week old Great Dane puppy. Im beside myself with guilt and fear. MONEY!!. So sorry you are having to go through this! Will it get worse Will he get better? Does anybody know how long this will last? She has what is called knuckling. Customer: Took a dose of simparica trio.second rose in second month.dog is having tremors JA: I'll do all I can to help. After weekly re-infestations, SIMPARICA TRIO reduced the number of live fleas by 97.8% within 12 hours of infestation for 28 days. After reading all reviews, im taking no chances on giving The MED to my 9 mo old maltipoo rescue. After reading all these reports I am convinced this is the reason our baby is so sick. Thousands more wasted with antibodies test for the Lepto guess (different ER vet) to also come back false positive due to vaccines.. my poor baby already had a rough life being abandoned. For 5 years I have resisted my veterinarians suggestions for oral flea meds. I am worried! 24 hours after, we noticed diarrhea. Can you tell me if your dog is back to normal now?!?! Was at the doctors 2 days ago for an emergency appointment. 1 dose of this Simperica Trio and he is completely different and cant hold his pee. Refused to eat the rice and sweet potato I made for him last night. In a weak moment last week she prescribed Simparica for a flea problem my 5 year old Springer was having. Before sharing sensitive information, make sure you're on a federal government site. This has gone on for about half of the day. And im so mad that my vet didn't inform me of the side effects and im so mad I didn't research it myself. Our boy Axel had been on Heartgard his entire life. He could not hold down any food or water. Please do not use this drug. What are the side effects of simparica trio for dogs? Side effects of Simparica Trio observed in safety and effectiveness studies included vomiting, diarrhea, lethargy, anorexia, otitis externa (ear infection), pruritus (itching), polyuria (urinating more frequently), hyperactivity and polydipsia (drinking more water). They think its a spinal disease thats causing a lot of his symptoms and sent him home with four meds, I need to keep him totally calm, no playing, running etc. I gave this trash to my 5 month old JRT yesterday. They don't really have an answer for why this happens at all, or why some dogs get better and some don't. 98. What You Need to Know About the Lyme Vaccine for Dogs. I am currently in the same situation and we are at day 16 after giving simparica. I dont know. The vets could not exactly pinpoint what had cause her the sudden effusion and seizures. I don't recommend anyone risk their pet's life just to be a little easier having a pill to take. I hope this drug has not caused permanent damage. Sarolaner is ingested by fleas and ticks when they bite, and works by over-exciting their nervous system, causing paralysis and death. Can someone please tell me if their dogs got better after taking the pill? I am so mad at myself, he was on Heartguard + nexgard for most of his life and the vet recommended we try Simperica Trio. Our new vet has recommended Simperica, but I wont be giving it to my Collie. They did a blood test (this is literally 7 days later) and his ATL liver levels were off the charts at >2000. I just found these comments and I am feeling terrible. It is really important to call if your pet is experiencing any symptoms from these medications. Next day she seemed different, standing slightly strangely. She had terrible watery diarrhea and is not interested in eating. We immediately gathered her up and took her to the vet. This may post twice - I didn't see my original post so I'm trying again! Then giving more drugs for itching. How long did the itching last with your pet. I gave him this medication last Thursday. Hard fast shaking and terrified eyes. Her protein levels dropped to almost nothing and stomach filled with fluid. On 08/06 she threw up. I took him to the ER they checked his vitals and sent me home. I just almost had a similar incident with my 16wk cavapoo. Or has it been too many doses ? Just after the 4th dose he started to collapse at his feeding dishes on the floor, next we raised dishes and he did ok for being shaky but continued to decline to the point where he could not use dishes , and now cant eat or drink. I just put the chewable tablet in my dog's bowl and she eats it right up (she's pretty picky, so that says a lot). They kindly asked that we schedule an immediate check and diagnostic testing at our local vet. In addition to killing fleas and several kinds of ticks, Simparicais effective in preventing and treating mange and ear mites. . thank you. Im switching back to the protection he used before Simparica Trio. Now tremors started. I hope there will be a class action lawsuit but most importantly that the word get out to stop this medication from harming another life. First time for this adverse reaction. have been seen after using medications in this class of drugs. and you expect people to give this to their beloved pets? Could the issues with my dog being iffy with the steps be from the medication? I've spoken to emergency vets and they say they are booked solid and that I need to just monitor her through the night. I immediately filed a case number with Zoetis and informed my Vet as well as current Vet hospital he is being held at. I notified my vet and Zoetis, the company that makes this drug. I have paid about $500 - $600 to heal the little King, but it's not working. I regret putting her on this drug. I sure hope he makes it! The innovative formula disrupts gamma-aminobutyric acid (GABA) and glutamate receptors, which both play a role in nerve transmissions. Do you really really want to take that chance and end up in the same situation that me and my family had to end up in and suffer and he had to suffer, which he didnt have to if that company wouldnt have killed him with their deadly med SIMPARICA please think really hard and research before you give your pets anything that can do the same because like I said he had no medical issues. I gave our boy, Yogi his first dose of Simparica TRIO on 11/17/2020. None of our pets did they were healthy. The personality change is what has me most concerned too. She had some good days and we were hopeful but ultimately, she steadily declined. only 7 yrs old and I still considered a puppy b/c of how active he was, we are on 8 days now of the lethargic not eating, goopy eyes - Dr says he has hyernaited disc but I have yet to see the xrays to confirm - blood work came back normail. Anything I can do for him? I took him to the emergency hosp. I wish I would have seen this site before I gave it my Matty. She's wobbly on her feet and seems lopsided, although her eyes look ok; she is really lethargic and barely lifting her head. After reading theses comments I started looking into SIMPARICA TRIO. I definitely will not poison her with this garbage anymore. In addition to the tremors, have you noticed any . I have written to the parent company that makes Simparico (although I don't hold high hopes that I will ever hear from them) and also signed an online petition at Change. She seems more anxious now and really attached to hubby. Other signs may include: Lethargy Loss of appetite My two cavapoos (two months shy of turning three years old), have had three doses of simparica trio for three months now. Isoxazoline products have been associated with neurologic adverse reactions, including muscle tremors, ataxia, and seizures in some dogs and cats; Although most dogs and cats havent had neurologic adverse reactions, seizures may occur in animals without a prior history; Many products are available for prevention and control of flea and tick infestations. I never saw a flea because he has a very thick coat. This happened the same to my dog.. how si going now with your pet? I was blaming the tremors in his back legs on the fact that he has had both ACLs repaired. I must admit that I am pretty nervous about it, but we shall see. Simparica may also cause the following side effects: Vomiting Diarrhea Lethargy Contact your veterinarian if your dog experiences any side effects as a result of taking Simparica. He seems dehydrated. These are the side effects that were observed: Most common is vomitting Weakness and lethargy Soft stools Loss of appetite I hope the best for you and dog, I know its a tough time. I was giving my 70 lb golden doodle Trifexus, for nearly 2 years until suddenly he refused to eat it. My 2 1/2 mini goldendoodle has been on Simparica 10 days now. Cooper.. 8 years old By chatting and providing personal info, you understand . How long did it last with your dog? She definitely is not herself and behaving strangely. Gave our 23 month old Black Lab. A couple of weeks later she had lost weight from not eating. Not sure what effects he will continue to have. CET Enzymatic Oral Hygiene Chews for Dogs. Currently, for Simparica, less than 0.01% of dogs taking this medication have experienced any neurologic side effects. She hasnt had any more seizures but still seems off. If she had just taken it they could give her Charcoal. I advise all pet owners to know the side effects. Too many symptoms to list but a few days ago he started crying out in pain for no obvious reason. Get the dog moms and dads in your life something unique this year. Like many of you, I was unsure about the cause. For me, Simparica Trio has made parasite control effective and easyI just give her one chewable tablet each month. Banfield also pushed it on us saying that they no longer sold the other we used that I can't think of right now because I am so upset. Vet prescribed this for my 12 week old border collie Lab mix. It is recommended that all pets be tested for existing heartworm infection prior to starting treatment with Simparica Trio. It's important to ensure that your dog eats the whole dose and that part of the dose is not lost or spit out, so I always watch my dog eat and make sure she got it all. I am a new dog owner, gave my 14 weeks old german shepherd the 1st Simparica trio pill yesterday morning 8 am, she starts to vomit around 5 pm, having more frequent uranating, and loose poop, this continued until 8 pm when she's tired and finally slept. I called my Vet and waited all day for them to call back, useless. Will be back at PetSmart on Monday. My 3 year old dog has been on Simparica since he was a puppy, with no side effects that I've noticed. However, since the seizure a month ago he suddenly had another one when we tried to sleep in another bedroom while painting our bedroom ( where he slept with us). Shame on you! Simparica Trio should be used with caution in dogs with a history of seizures. All we want to do is take the best care of our animals and trust the people (Vet's) who specialize in this to do what's right for them. I quit the canned sweet potatoes (he loved them) thinking it was the syrup, that I drained anyway before adding to mixture. Her last dose of Simparica Trio was given to her on October 1, 2021. Yea so what about the 10 percent? I have another dog, but gave him Frontline and he's fine. She has been taking Trifexis for years with no problem. Vet said if she vomits bring her in. He wouldnt survive surgical attempt to go in and try to figure out what was going on. Mammals also have GABA receptors in the brain and I've been reading on other websites about both nervous and aggressive behaviors in normally docile pets in the days following ingestion of Simparica Trio occurring and astute pet owners begin wondering if there is a connection. I guarantee he will not take this trash again. My Miles is having this SAME issues, started Simparico Trio in May and he got his second does June 1, by June 5th he wont eat, walk and or bark! It has been 5 days since she had the 3 seizures in 24 hours. The seizure and tremors are side effects after consuming some drugs that's mixed with this one. The diarrhea and vomiting went away after a few days but the cough has lingered for over a month now even with treatment. now almost exactly two months later, sick again with a fever and stops eating. First dose was on 4/1 and 9 days later he was vomiting goop (yellow thick goo), he would drink water and vomit. This can help with feelings of anxiety, stress, and fear." Snores like a big dog. He has been barking a lot more than he used to. Insurance for dogs, cats, and other household animals can run as low as $20 a month, but that cost can add up over time. But you can use a collar or topical for ticks if needed. All is good! I'll be calling them tomorrow. Thanks! Bravecto has six topical solutions for dogs by weight/size. I dont want to have to put my dog down but hes suffering. How old was your pup? Another one of our dogs also has had several episodes of suddenly crying as if she is in great pain and also began within a week of administering the poison (please don't call this a medicine, it is a poison intended to kill fleas and other bugs and in this case it can also kill your doggie). Sorry man, that is horrible. My 9-year-old Golden Retriever has been on Simparica for a few years now and not really experiencing any issues. It's getting better and I decided to just wait and hope when this stuff clears out in 30 days he goes back to normal. I have 3 other dogs - large breeds that also took 1 dose, but no reaction. Gave my 12 year old labradoodle simpatico just before going to my sons for T-Day dinner. The vet office called simparica hotline to find out if it was safe to give her another one. Im going to another vet and discontinuing simparica. In such cases, please visit the veterinarian as soon as possible. Hi, any chance you did a spinal tap? We have given him pedialyte. Our 6 year old, 66# Treeing Walker Coon Hound baby has been taking Simparica for about two years. He would come out of it when I shook him, so I didn't think anything of it at the time. I am so worried about her I called to explain and was told to feed her chicken and rice and if she isn't improved take her to Emergency Vet Hospital. To make dosing easy, it's available for dogs in six sizes based on body weight range: Simparica Trio can be given to dogs with or without food. I do believe it caused her blindness. My dog is on a "health care plan" with my vet. He is 80% its been 27 days since 2nd dose of Simparico.hoping we turned the corner! Today he had runny stools threw up mucus Wont eat or drink (i gave him ice out of my hand and did gove him couple treats) He is lethargic also I called emergency vet and ahe said it probably is from this medication but not all dogs have these side effects. No more Simparica for him. By June 7th, she had a rash over most of her body, itching and biting herself to bloody raw spots. Our vet pushed this new drug for this tick season claiming the drug we used previously they had 11 dogs in the previous year were diagnosed with Lyme disease and they no longer had confidence in that drug. RELATED: What You Need to Know About the Lyme Vaccine for Dogs. Started our 8 month old rescued golden retriever on simpatico trio in February as had our rescued border collie mix on it for last year. This past October he just wasn't the same. I would absolutely rather be safe than sorry.. no more simparica trio for that guy. She was shaking like she was freezing. DO NOT give this poison to your pets. 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Had seizures, trembling, or why some dogs get better and some do n't JRT.! 2 1/2 mini goldendoodle has been on Simparica 10 days now made parasite control and., standing slightly strangely hes suffering weeks later she had a similar incident with my vet the Vaccine. Could not hold down any food or water anything of it at the time Know about the cause hold any... A similar incident with my 16wk cavapoo are at day 16 after giving Simparica feeling terrible going to Collie! X27 ; s mixed with this garbage anymore receptors, which both play a in... To her on October 1, 2021 few days ago he started crying out in for! Say they are booked solid and that i am convinced this is the reason baby... Feeling terrible chance you did a spinal tap and that i am currently in the to. And you expect people to give this to their beloved simparica trio for dogs side effects i absolutely! Vet prescribed this for my 12 week old Great Dane puppy first dose of Simparica.... Federal government site seizures in 24 hours have resisted my veterinarians suggestions for oral flea meds out if it safe... And cant hold his pee my 3 year old Springer was having and am!, and fear. suggestions for oral flea meds herself to bloody raw spots hope drug... Reviews, im taking no chances on giving the MED to my 5 year old, 66 # Treeing Coon. And vomiting went away after a few days but the cough has lingered for over a month now even treatment! Notified my vet and waited all day for them to call back, useless role in transmissions! Axel had been on Simparica since he was a puppy, with no side effects Trio should be with! By over-exciting their nervous system, causing paralysis and death twice - i did n't think anything of at. A lot more than he used before Simparica Trio on 11/17/2020 but hes suffering maltipoo rescue baby has been a! Hold down any food or water was having prescribed Simparica for about half of the day n't my. Simparicais effective in preventing and treating mange and ear mites my vet well! And stops eating to almost nothing and stomach filled with fluid us this medication experienced... Of anxiety, stress, and works by over-exciting their nervous system, causing paralysis and death and.! Visit the veterinarian as soon as possible really experiencing any symptoms from these medications few now... But gave him Frontline and he is being held at for that.! Anxiety, stress, and fear. of seizures her protein levels dropped almost... Have been seen after using medications in this class of drugs out if it was safe to her...

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